Fredric March
Marcus Superbus - Prefect of Rome
Elissa Landi
Mercia
Claudette Colbert
Empress Poppaea
Charles Laughton
Emperor Nero Claudius Caesar
Ian Keith
Tigellinus
Arthur Hohl
Titus
Harry Beresford
Favius Fontelas
Tommy Conlon
Stephan
Ferdinand Gottschalk
Glabrio
Vivian Tobin
Dacia
William V. Mong
Licinius
Joyzelle Joyner
Ancaria
Richard Alexander
Viturius
Nat Pendleton
Strabo
Clarence Burton
Servillius
Harold Healy
Tybul
Robert Seiter
Philodemus
Charles Middleton
Tyros
Henry Brandon
Colosseum Spectator (uncredited)
John Carradine
Christian Martyr / Gladiator Leader / Voice in Coliseum Mob (uncredited)
Dave O'Brien
Christian on Stairway (uncredited)
Sally Rand
Crocodiles' Victim (uncredited)
Arthur Shields
Chaplain Costello (1944 Re-Release Prologue) (uncredited)
Tom Tully
Hoboken (1944 Re-Release Prologue) (uncredited)
Lionel Belmore
Bettor of 300 Silver
Ynez Seabury
Little Girl
Cecil B. DeMille
Director
Waldemar Young
Screenplay
Sidney Buchman
Screenplay
Wilson Barrett
Theatre Play
Cecil B. DeMille
Producer
Jay Chernis
Music
Rudolph G. Kopp
Music
Paul Marquardt
Music
Milan Roder
Music
Karl Struss
Director of Photography
Anne Bauchens
Editor
Mitchell Leisen
Art Direction
Mitchell Leisen
Costume Design
James Collins
Makeup Artist
Roy Burns
Production Manager
Mitchell Leisen
Assistant Director
Edward Salven
Assistant Director
Treg Brown
Sound Effects Editor
Harry Lindgren
Sound
Otto Dyar
Still Photographer